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PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

PI 3-Kinase Signaling in Disease (Z3)

Apr 22-27, 2009 at Resort at Squaw Creek, Olympic Valley California United States

The PI 3-kinase signaling pathway controls multiple physiological processes including cell growth, cell proliferation and cell movement. Dysregulation of this pathway in cancer, inflammation and heart disease has led to the emergence of PI 3-kinase as a promising therapeutic target. One of the most exciting developments in this field is the discovery of new PI 3-kinase inhibitors. The balance between modulating PI 3-kinase activity in pathophysiological setting, whilst avoiding unwanted side-effects, is the subject of intense debate. In addition, as PI 3-kinase is a member of a multigene family, the rationale for inhibiting individual isoforms or multiple isoforms of PI 3-kinase is constantly changing. This meeting aims to bring together scientists and clinicians from academia and industry to discuss the opportunities and liabilities of targeting the PI 3-kinase pathway in disease, drawing on human pathophysiology and genetics, mouse models and preclinical data with new PI 3-kinase inhibitors.

Complex Lipids in Biology: Signaling, Compartmentalization and Disease (Z4)

Apr 22-27, 2009 at Resort at Squaw Creek , Olympic Valley California United States

Complex lipids constitute a diverse family of biomolecules of seven general classes that serve essential roles in Biology. For example, lipids include structural phospholipids that form cellular membranes but are also the reservoirs and source of polyunsaturated fatty acids that are signaling mediators. Intense research effort over the past years has substantially changed our understanding of lipid biochemistry and lipid function in cells with the application of new tools and techniques to study these molecules. This meeting will bring together a group of individuals who have the common goal of understanding the role that lipids play in cell biology, physiology and disease processes.

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